PUBBLICAZIONI
DOTTOR STEFANO FRACCHIOLI
Dr. Stefano Fracchioli
LE PUBBLICAZIONI
Oltre 30 pubblicazioni su prestigiose riviste scientifiche internazionali derivate dall’attività di ricerca svolta in abito di ginecologia oncologica presso l’Università degli Studi di Torino e l’Istituto per la Ricerca e la Cura del Cancro (IRCC) di Candiolo, anche in collaborazione con importanti laboratori di USA e Canada.
01
Fracchioli S, Puopolo M, De La Longrais IA, Scozzafava M, Bogliatto F, Arisio R, Micheletti L, Katsaros D. Primary “breast-like” cancer of the vulva: a case report and critical review of the literature. Int J Gynecol Cancer. 2006 Jan-Feb;16 Suppl 1:423-8. Review. PubMed PMID: 16515638.
02
Wiley A, Katsaros D, Fracchioli S, Yu H. Methylation of the insulin-like
growth factor binding protein-3 gene and prognosis of epithelial ovarian cancer.
Int J Gynecol Cancer. 2006 Jan-Feb;16(1):210-8. PubMed PMID: 16445635.
03
Beeghly A, Katsaros D, Chen H, Fracchioli S, Zhang Y, Massobrio M, Risch H, Jones B, Yu H. Glutathione S-transferase polymorphisms and ovarian cancer treatment and survival. Gynecol Oncol. 2006 Feb;100(2):330-7. Epub 2005 Sep 29. PubMed PMID: 16199080.
04
Zhang L, Yang N, Huang J, Buckanovich RJ, Liang S, Barchetti A, Vezzani C, O’Brien-Jenkins A, Wang J, Ward MR, Courreges MC, Fracchioli S, Medina A, Katsaros D, Weber BL, Coukos G. Transcriptional coactivator Drosophila eyes absent homologue 2 is up-regulated in epithelial ovarian cancer and promotes tumor growth. Cancer Res. 2005 Feb 1;65(3):925-32. PubMed PMID: 15705892.
05
Katsaros D, Oletti MV, Rigault de la Longrais IA, Ferrero A, Celano A, Fracchioli S, Donadio M, Passera R, Cattel L, Bumma C. Clinical and pharmacokinetic phase II study of pegylated liposomal doxorubicin and vinorelbine in heavily pretreated recurrent ovarian carcinoma. Ann Oncol. 2005 Feb;16(2):300-6. PubMed PMID: 15668288.
06
Katsaros D, Cho W, Singal R, Fracchioli S, Rigault De La Longrais IA, Arisio R, Massobrio M, Smith M, Zheng W, Glass J, Yu H. Methylation of tumor suppressor gene p16 and prognosis of epithelial ovarian cancer. Gynecol Oncol. 2004 Sep;94(3):685-92. PubMed PMID: 15350359.
07
Porpiglia M, Vicelli R, Durando A, Fracchioli S, Puopolo M, Katsaros D, Bellino R, Benedetto C. [Biologic therapy and epithelial ovarian cancer]. Minerva Ginecol. 2004 Feb;56(1):91-104. Review. Italian. PubMed PMID: 14973413.
08
Borgoño CA, Grass L, Soosaipillai A, Yousef GM, Petraki CD, Howarth DH, Fracchioli S, Katsaros D, Diamandis EP. Human kallikrein 14: a new potential biomarker for ovarian and breast cancer. Cancer Res. 2003 Dec 15;63(24):9032-41. PubMed PMID: 14695222.
09
Yousef GM, Scorilas A, Katsaros D, Fracchioli S, Iskander L, Borgono C, Rigault de la Longrais IA, Puopolo M, Massobrio M, Diamandis EP. Prognostic value of the human kallikrein gene 15 expression in ovarian cancer. J Clin Oncol. 2003 Aug 15;21(16):3119-26. PubMed PMID: 12915603.
10
Maggiora P, Lorenzato A, Fracchioli S, Costa B, Castagnaro M, Arisio R, Katsaros D, Massobrio M, Comoglio PM, Flavia Di Renzo M. The RON and MET oncogenes are co-expressed in human ovarian carcinomas and cooperate in activating invasiveness. Exp Cell Res. 2003 Aug 15;288(2):382-9. PubMed PMID: 12915129.
11
Zhang L, Yang N, Katsaros D, Huang W, Park JW, Fracchioli S, Vezzani C, Rigault de la Longrais IA, Yao W, Rubin SC, Coukos G. The oncogene phosphatidylinositol 3′-kinase catalytic subunit alpha promotes angiogenesis via vascular endothelial growth factor in ovarian carcinoma. Cancer Res. 2003 Jul 15;63(14):4225-31. PubMed PMID: 12874030.
12
Borgoño CA, Fracchioli S, Yousef GM, Rigault de la Longrais IA, Luo LY, Soosaipillai A, Puopolo M, Grass L, Scorilas A, Diamandis EP, Katsaros D. Favorable prognostic value of tissue human kallikrein 11 (hK11) in patients with ovarian carcinoma. Int J Cancer. 2003 Sep 10;106(4):605-10. PubMed PMID: 12845660.
13
Zhang L, Yang N, Park JW, Katsaros D, Fracchioli S, Cao G, O’Brien-Jenkins A, Randall TC, Rubin SC, Coukos G. Tumor-derived vascular endothelial growth factor up-regulates angiopoietin-2 in host endothelium and destabilizes host vasculature, supporting angiogenesis in ovarian cancer. Cancer Res. 2003 Jun 15;63(12):3403-12. PubMed PMID: 12810677.
14
Fracchioli S, Porpiglia M, Arisio R, Voglino G, Katsaros D. Oral squamous carcinoma in a patient with cervix cancer: use of human papillomavirus analysis to differentiate synchronous versus metastatic tumor. Gynecol Oncol. 2003 Jun;89(3):522-5. PubMed PMID: 12798722.
15
Yousef GM, Polymeris ME, Yacoub GM, Scorilas A, Soosaipillai A, Popalis C, Fracchioli S, Katsaros D, Diamandis EP. Parallel overexpression of seven kallikrein genes in ovarian cancer. Cancer Res. 2003 May 1;63(9):2223-7. PubMed PMID: 12727843.
16
Yousef GM, Fracchioli S, Scorilas A, Borgoño CA, Iskander L, Puopolo M, Massobrio M, Diamandis EP, Katsaros D. Steroid hormone regulation and prognostic value of the human kallikrein gene 14 in ovarian cancer. Am J Clin Pathol. 2003 Mar;119(3):346-55. PubMed PMID: 12645335.
17
Diamandis EP, Scorilas A, Fracchioli S, Van Gramberen M, De Bruijn H, Henrik A, Soosaipillai A, Grass L, Yousef GM, Stenman UH, Massobrio M, Van Der Zee AG, Vergote I, Katsaros D. Human kallikrein 6 (hK6): a new potential serum biomarker for diagnosis and prognosis of ovarian carcinoma. J Clin Oncol. 2003 Mar 15;21(6):1035-43. PubMed PMID: 12637468.
18
Kyriakopoulou LG, Yousef GM, Scorilas A, Katsaros D, Massobrio M, Fracchioli S, Diamandis EP. Prognostic value of quantitatively assessed KLK7 expression in ovarian cancer. Clin Biochem. 2003 Mar;36(2):135-43. PubMed PMID: 12633763.
19
Luo LY, Katsaros D, Scorilas A, Fracchioli S, Bellino R, van Gramberen M, de Bruijn H, Henrik A, Stenman UH, Massobrio M, van der Zee AG, Vergote I, Diamandis EP. The serum concentration of human kallikrein 10 represents a novel biomarker for ovarian cancer diagnosis and prognosis. Cancer Res. 2003 Feb 15;63(4):807-11. PubMed PMID: 12591730.
20
Zhang L, Yang N, Conejo-Garcia JR, Katsaros D, Mohamed-Hadley A, Fracchioli S, Schlienger K, Toll A, Levine B, Rubin SC, Coukos G. Expression of endocrine gland-derived vascular endothelial growth factor in ovarian carcinoma. Clin Cancer Res. 2003 Jan;9(1):264-72. PubMed PMID: 12538479.
21
Hoffman BR, Katsaros D, Scorilas A, Diamandis P, Fracchioli S, Rigault de la Longrais IA, Colgan T, Puopolo M, Giardina G, Massobrio M, Diamandis EP. Immunofluorometric quantitation and histochemical localisation of kallikrein 6 protein in ovarian cancer tissue: a new independent unfavourable prognostic biomarker. Br J Cancer. 2002 Sep 23;87(7):763-71. PubMed PMID: 12232761; PubMed Central PMCID: PMC2364256.
22
Piccinno R, Puopolo M, Rigault De La Longrais IA, Fracchioli S, Massobrio M, Katsaros D. [Growth factors in epithelial ovarian cancer]. Minerva Ginecol. 2002 Feb;54(1):33-52. Review. Italian. PubMed PMID: 11828269.
23
Katsaros D, Yu H, Piccinno R, Puopolo M, Rigault De La Longrais IA, Fracchioli S, Massobrio M. [Expression and prognostic significance in epithelial ovarian cancer]. Minerva Ginecol. 2002 Feb;54(1):15-24. Italian. PubMed PMID: 11828267.
24
Yousef GM, Kyriakopoulou LG, Scorilas A, Fracchioli S, Ghiringhello B, Zarghooni M, Chang A, Diamandis M, Giardina G, Hartwick WJ, Richiardi G, Massobrio M, Diamandis EP, Katsaros D. Quantitative expression of the human kallikrein gene 9 (KLK9) in ovarian cancer: a new independent and favorable prognostic marker. Cancer Res. 2001 Nov 1;61(21):7811-8. PubMed PMID: 11691797.
25
Obiezu CV, Scorilas A, Katsaros D, Massobrio M, Yousef GM, Fracchioli S, Rigault de la Longrais IA, Arisio R, Diamandis EP. Higher human kallikrein gene 4 (KLK4) expression indicates poor prognosis of ovarian cancer patients. Clin Cancer Res. 2001 Aug;7(8):2380-6. PubMed PMID: 11489816.
26
Luo LY, Katsaros D, Scorilas A, Fracchioli S, Piccinno R, Rigault de la Longrais IA, Howarth DJ, Diamandis EP. Prognostic value of human kallikrein 10 expression in epithelial ovarian carcinoma. Clin Cancer Res. 2001 Aug;7(8):2372-9. PubMed PMID: 11489815.
27
Magklara A, Scorilas A, Katsaros D, Massobrio M, Yousef GM, Fracchioli S, Danese S, Diamandis EP. The human KLK8 (neuropsin/ovasin) gene: identification of two novel splice variants and its prognostic value in ovarian cancer. Clin Cancer Res. 2001 Apr;7(4):806-11. PubMed PMID: 11309326.
28
Katsaros D, Yu H, Levesque MA, Danese S, Genta F, Richiardi G, Fracchioli S, Khosravi MJ, Diamandi A, Gordini G, Diamandis EP, Massobrio M. IGFBP-3 in epithelial ovarian carcinoma and its association with clinico-pathological features and patient survival. Eur J Cancer. 2001 Mar;37(4):478-85. PubMed PMID: 11267857.
29
Kim H, Scorilas A, Katsaros D, Yousef GM, Massobrio M, Fracchioli S, Piccinno R, Gordini G, Diamandis EP. Human kallikrein gene 5 (KLK5) expression is an indicator of poor prognosis in ovarian cancer. Br J Cancer. 2001 Mar 2;84(5):643-50. PubMed PMID: 11237385; PubMed Central PMCID: PMC2363783.
30
Levesque MA, Katsaros D, Massobrio M, Genta F, Yu H, Richiardi G, Fracchioli S, Durando A, Arisio R, Diamandis EP. Evidence for a dose-response effect between p53 (but not p21WAF1/Cip1) protein concentrations, survival, and responsiveness in patients with epithelial ovarian cancer treated with platinum-based chemotherapy. Clin Cancer Res. 2000 Aug;6(8):3260-70. PubMed PMID: 10955812.
31
Katsaros D, Fracchioli S, Arese P, Enria R, Cassinelli P, Mingrone K, Piccinno R, Rigault de la Longrais IA, Massobrio M. [Chemoresistance in ovarian cancer. State of the art and future prospects]. Minerva Ginecol. 1999 Dec;51(12):483-99. Review. Italian. PubMed PMID: 10767997.
32
Katsaros D, Fracchioli S, Arts HJ, de Vries EG, Danese S, Richiardi G, Arisio R, Gordini G, Van der Zee AG, Suurmeijer AJ, Massobrio M. [Expression and prognostic value of the drug resistance markers P-gp, Mrp1, Mrp2, and Lrp in ovarian carcinoma]. Minerva Ginecol. 1999 Dec;51(12):463-70. Italian. PubMed PMID: 10767994.
33
Fracchioli S, Katsaros D, Maggiora P, Di Renzo MF, Massobrio M. [Evaluation of Ron and Met proto-oncogene expression in epithelial ovarian tumors]. Minerva Ginecol. 1999 Oct;51(10):359-64. Italian. PubMed PMID: 10638160.
